PRE CLINICAL RESEARCH

Protective effects with 100mg/kg of BioKesum™ and do not show scopolamine induced deficit in learning and memory (equivalent to donepezil) and Gingko biloba. This effect is further validated in two clinical trials looking into cognitive function and memory in healthy subjectsReference: George A, Ng CP, O’Callaghan M, Jensen GS, Wong HJ. In vitro and ex-vivo cellular antioxidant protection and cognitive enhancing effects of an extract of Polygonum minus Huds demonstrated in a Barnes Maze animal model for memory and learning. BMC Complement Altern Med. 2014 May 19;14:161. doi: 10.1186/1472-6882-14-161.

CLINICAL RESEARCH

References:
‍
Study 1: Shahar S, Aziz AF, Ismail SNA, et al. The effect of Polygonum minus extract on cognitive and psychosocial parameters according to mood status among middle-aged women: a randomized, double-blind, placebo-controlled study. Clinical Interventions in Aging. 2015;10:1505-1520. doi:10.2147/CIA.S86411.

Study 2: Jay K Udani, “Effects of SuperUlam on Supporting Concentration and Mood: A Randomized, Double-Blind, Placebo-Controlled Crossover Study,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 238454, 10 pages, 2013. doi:10.1155/2013/238454

HIGH IN ANTIOXIDANT

Kesum have been shown to have the highest total phenolic content amongst other ‘Ulam’ (salad) plants (Maizura, et. al., 2011). BioKesum™ shows strong antioxidant properties that slow the oxidative processes and free radical damage such as:

Reference:

Maizura, M., Aminah, A. and Wan Aida, W. M. Total phenolic content and antioxidant activity of kesum (Polygonum minus), ginger (Zingiber officinale) and turmeric (Curcuma longa) extract. International Food Research Journal 18: 529-534 (2011).

iv class=”about-us-content”>George A, Ng CP, O’Callaghan M, Jensen GS, Wong HJ. In vitro and ex-vivo cellular antioxidant protection and cognitive enhancing effects of an extract of Polygonum minus Huds (Lineminus™) demonstrated in a Barnes Maze animal model for memory and learning. BMC Complement Altern Med. 2014 May 19;14:161. doi: 10.1186/1472-6882-14-161